Adenosine Deaminase, CSF: 35703-8 * Component test codes cannot be used to order tests. The ADA test gave a sensitivity of 82% and a specificity of 83% for infectious TBM when this cut-off value was used. Synonyms. Adenosine Deaminase, CSF - An elevated level of adenosine deaminase (AD) in human serum, plasma or select body fluids is used as a surrogate marker for inflammation or infectious disease. ADA; Adenosine Deaminase in CSF. CONCLUSION: This study demonstrated that ADA activity in the CSF of TBM patients, using a cut-off value 11.39 U/L/min, can be useful for the early differential diagnosis of TBM. Conclusion: This study demonstrated that ADA activity in the CSF of TBM patients, using a cut-off value 11.39 U/L/min, can be useful for the early differential diagnosis of TBM. A CSF analysis is a group of tests that evaluate substances in CSF in order to diagnose conditions affecting the brain and spinal cord (central nervous system). In the present study we measured the adenosine deaminase (ADA) activity in cerebrospinal fluid (CSF) of TBM and non-TBM patients. Method: ADA activity in CSF was determined… CONTINUE READING The ADA test gave a sensitivity of 82% and a specificity of 83% for infectious TBM when this cut-off value was used. The ADA test is used as an additional test to help rule in or rule out tuberculosis in pleural fluid. ... Other names that describe the test. ADA is an enzyme involved in purine metabolism and it is essential for the proliferation and differentiation of T-lymphoid cells. Rarely, it may be requested to detect tuberculosis in other body fluids, such as peritoneal fluid or cerebrospinal fluid (CSF… CSF is formed and secreted by the choroid plexus, a special tissue that has many blood vessels and that lines the small cavities or chambers (ventricles) in the brain. In CSF, pleural effusions, and pericardial fluid in particular, elevated AD activity has been shown to be associated with tubercular lesions. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map. ADA test along with other tests such as AFB smear, culture, fluid analysis, molecular testing with NAAT etc, helps to determine if there is tuberculous infection. Feedback . Similarly CSF ADA results for the ‘Confirmed TBM’ category were compared to all CSF ADA results for patients where culture for Mycobacterium tuberculosis complex (TB) on CSF was either not requested or negative, i.e. Despite ADA test has high sensitivity and specificity, the diagnostic value of CSF ADA remains to be explored. There is a need for a simple and fast laboratory test to differentiate TBM from other causes. Aims Tuberculous meningitis (TBM) is a severe infection which may lead to serious complication and mortality. Feedback. A reliable, cost effective and rapid diagnostic test, which can be performed in any routine laboratory, could be of help in the diagnosis of TBM. on the total population for this study (n = 3548). Background: Tuberculous meningitis (TBM) is often under and over diagnosed, thereby making the ancillary diagnostic tests important for establishing the diagnosis of TBM.The objective of this study was to evaluate cerebrospinal fluid adenosine deaminase (CSF-ADA) as an ancillary test for the diagnosis of TBM, and further, its correlation with adverse neurological outcome in these patients. It is necessary to interpret the ADA result with the combination of clinical symptoms and laboratory results. Pleural fluid rule out tuberculosis in pleural fluid fast laboratory test to help rule in or rule out tuberculosis pleural... 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